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Student Led Research

Vol. 1 No. 2 (2023): Magnified and In Focus

A 44-Year-Old Man with a Sore Throat and Vesicular Rash

May 5, 2023


Mpox (formerly known as monkeypox) is a rare viral disease with a presentation similar to smallpox, caused by the mpox virus (MPXV). Mpox outbreaks have been reported in Africa, and there have been sporadic cases in other parts of the world, including the United States. Immunocompromised individuals, including those with HIV, are at greater risk for more severe disease. Here we present a case of a 44-year-old HIV-positive male with a recent history of sexual activity with other men, who presented with tonsillitis and a vesicular rash. The presentation was highly concerning for mpox, and a PCR test ultimately returned positive for the mpox virus. The patient was started on supportive care, antibiotics, and antiviral therapy. 


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